Protocol for Macrophage Depletion from Mice

Protocol for Macrophage Depletion from Mice

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Macrophage depletion has been used extensively to study autoimmune disease and more recently in tumor models.The clodronate-containing liposomes will be recognized as foreign particles and get engulfed by BENGAL SPICE macrophages upon dosing into the animal by the chosen routes.Consequently, macrophages that have Heel Balm engulfed liposomes will all be destroyed by the liposomal.

In the protocol presented here the clodronate-containing liposomes were used to systemically deplete macrophages in mice.